Our platform offers state-of the art large histotechnological laboratory with a specialized team. We are available for collaborative research. Many projects are currently ongoing on animal models of infectious diseases, cancer, immunotherapy or inflammation with internal or external research teams. Individuals wishing to develop collaborative research efforts are encouraged to contact uswhen developing research projects. Optimal results are obtained when the staff is contacted as early as possible in the conception of the in vivo part of the project; this allows us to help determine how histological approach can best support the research aim.
For Histology requests, training or reserve a system:PPMS
Range of services
A variety of histology services can be provided to research investigators:
Necropsy & gross examination of animal tissues
Design of the protocol
Methodology advice on proper tissue collection
Choice of morphological approaches (fixation, embedding, slide preparation, slide treatments)
Evaluation of the slides
Histological and morphometric analyze
Fine tuning of Histopathology protocols
Discussion of the results
Recommendations for further experiments
Technics
Our Histology laboratory prepares slides and a wide variety of quality, flexible histopathological and immunohistochemical stains for investigative staff. We also develop new technical tools for animal tissue analysis:We also have access to Safety level 3 facility for frozen sectioning of infected human or animal tissues.
Access protocol
Sample process :
Equipment :
Terms of collaboration/authorship
Engineers and Pathologists who contributed to the project must be listed as co-authors and Technicians in acknowledgement.
Spatial Biology was specifically developed to analyze the enormous data stacks obtained by the MACSima™ Platform, allowing scientists to tap the full potential of spatial biology. Its versatility and intuitive user interface make it […]
At the heart of the MACSima Platform is the highly automated MACSima System, which combines high-plex spatial protein profiling with RNA detection on the same tissue section. Choose from compact panels of 15-20 protein […]
With smooth movement of the sledge, precision specimen orientation, and emphasis on safety and ergonomics, the SM2010 R produces high quality sections for routine histopathology (paraffin).The stable sliding microtome has a totally enclosed micrometer […]
The Axio Scan 7 allow to digitize histological sections and create high-quality virtual slides. Both bright field and fluorescent sections can be digitalized. Virtual slides can be then be kept and observed or used […]
This material is needed to perform frozen sections. People trained in frozen sectioning from other laboratories can use this material under our supervision. Please contact us
BOND RX fully automated research stainer Make that next big breakthough with confidence. From IHC to ISH, FISH, CTC, Multiplexing and more, the BOND RX provides research labs with an easy way to quickly […]
This material is needed for routinely dehydration and pre-embedding of tissue samples in paraffin. We can perform the pre-embedding of your tissue samples Please contact us if needed
High quality bright field microphotographs can taken with this material, which is connected to a NIKON 50i microscope. People from other laboratories can have access to this equipment Please contact us if needed
Vibrating microtomes (vibratomes) allows to cut tissues without freezing or embedding. 50-100 um sections can be performed to study the tissue morphology in 3D or to preserve enzyme and cell activities within thick slices. […]
This material is needed to perform frozen sections. People trained in frozen sectioning from other laboratories can use this material under our supervision. Please contact us
This automat provides reproducible automated, high quality standard stainings for paraffin or frozen histological sections. Please contact us if you need to stain histological sections (Hematoxylin-Eosin or special stains) Please contact us if needed
A microtome is needed to perform paraffin sections. Trained people from other laboratories can have access to this equipment under our supervision Please contact us if needed
The paraffin embedding station is needed to routinely prepare paraffin blocks. We can perform the embedding of your tissue samples Please contact us if needed
The Axio Scan allow to digitize histological sections and create high-quality virtual slides. Both bright field and fluorescent sections can be digitalized. Virtual slides can be then be kept and observed or used for […]
2024-10-07 09:00:002024-10-11 16:00:00Europe/ParisIntroduction to the basics of Histology and ImmunostainingProgramInstitut Pasteur, Rue du Docteur Roux, Paris, FranceAdd to Calendar
2023-10-09 09:00:002023-10-13 16:00:00Europe/ParisIntroduction to the basics of Histology and ImmunostainingObjectives : – Acquire basics in histology in order to know the sample preparation process – Know the different principles of histology – Understand immunochemistry & immunofluorescence techniques Program : – Sample preparation – […]28 Rue du Docteur Roux, Paris, FranceAdd to Calendar